Cellulite is caused due to distorted fats in the adipose and connective tissues. Exact reason for cellulite formation is not revealed yet. People believed that it is caused due to weight loss and sexual dimorphic traits. Cellulite is believed to involve in changes in the structure of the adipocyte and the surrounding septa, which are more vertically oriented, and allows movement of the adipocyte up to the dermis. Various studies were conducted to study the receptors that are involved in cellulite formation. Some of the receptors that are found in cellulite formation include; peroxisome proliferator activated receptors, uncoupling protein 1, and α-androgen receptors and β-androgen receptors. By analyzing these factors, scientists believed to find easy and long term result to cure cellulite.
The current trend followed in cellulite treatment involves heating adipocytes, remodeling it, and cause dermal remodeling in the septa surrounding the adipocyte cells. Bipolar radiofrequency power and infrared energy with vacuum and mechanical massage method is used in VelaShape for circumferential reduction of cellulite. TriActive, a FDA approved device combines a low-energy diode laser with suction massage to treat cellulite. Similarly Accent, also a FDA approved device uses dual radiofrequency technology for circumferential reduction. The unipolar setting is more effective than bipolar because it penetrates deep dermal and subdermal layers and treats large volume of tissues. SmoothShapes, another FDA recommended tool is also useful in treating cellulite. It combines a laser and an LED light source with mechanical rollers and a vacuum to restructure adipocytes and improve metabolism.
So in the mere future, there are many in and out approaches going to evolve for treating cellulite. Some expected techniques like combining external technologies with internal laser lipolysis to heat adipocytes and eat up septa which provides long term results. Mesotherapy is one method where drugs are injected to eliminate fat and improve metabolic activities in the adipocytes. Some of the mesotherapeutic ingredients are aminophylline, isoproterenol, ephedrine, calcium pyruvate, carnitine, and ma huang. Some detergents like phosphatidylcholine and deoxycholate can also be used in treating cellulite. Retinol Anti-Cellulite, a cosmeceutical from RoC, as well as electrolipolysis, carboxytherapy, and cryolipolysis are expected to be the further treatment methods in the mere future.
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